Detalhe da pesquisa
1.
A novel smaller ß-defensin-derived peptide is active against multidrug-resistant bacterial strains.
FASEB J
; 35(12): e22026, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34818435
2.
Host defense peptide-derived privileged scaffolds for anti-infective drug discovery.
J Pept Sci
; 23(4): 303-310, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28078813
3.
Dramatic potentiation of the antiviral activity of HIV antibodies by cholesterol conjugation.
J Biol Chem
; 289(50): 35015-28, 2014 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25342747
4.
Cholesterol-conjugated peptide antivirals: a path to a rapid response to emerging viral diseases.
J Pept Sci
; 21(5): 379-86, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25331523
5.
Cholesterol conjugation potentiates the antiviral activity of an HIV immunoadhesin.
J Pept Sci
; 21(9): 743-9, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26292842
6.
Improvement of HIV fusion inhibitor C34 efficacy by membrane anchoring and enhanced exposure.
J Antimicrob Chemother
; 69(5): 1286-97, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24464268
7.
Fatal measles virus infection prevented by brain-penetrant fusion inhibitors.
J Virol
; 87(24): 13785-94, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24109233
8.
Development of a neuromedin U-human serum albumin conjugate as a long-acting candidate for the treatment of obesity and diabetes. Comparison with the PEGylated peptide.
J Pept Sci
; 20(1): 7-19, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24222478
9.
A PEGylated analog of the gut hormone oxyntomodulin with long-lasting antihyperglycemic, insulinotropic and anorexigenic activity.
Bioorg Med Chem
; 21(22): 7064-73, 2013 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24094437
10.
Vaccination with peptide mimetics of the gp41 prehairpin fusion intermediate yields neutralizing antisera against HIV-1 isolates.
Proc Natl Acad Sci U S A
; 107(23): 10655-60, 2010 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-20483992
11.
Capturing a fusion intermediate of influenza hemagglutinin with a cholesterol-conjugated peptide, a new antiviral strategy for influenza virus.
J Biol Chem
; 286(49): 42141-42149, 2011 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-21994935
12.
Infection of primary neurons mediated by nipah virus envelope proteins: role of host target cells in antiviral action.
J Virol
; 85(16): 8422-6, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21653662
13.
Spring-loaded model revisited: paramyxovirus fusion requires engagement of a receptor binding protein beyond initial triggering of the fusion protein.
J Virol
; 85(24): 12867-80, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21976650
14.
Inhibition of Nipah virus infection in vivo: targeting an early stage of paramyxovirus fusion activation during viral entry.
PLoS Pathog
; 6(10): e1001168, 2010 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21060819
15.
PEGylation of Neuromedin U yields a promising candidate for the treatment of obesity and diabetes.
Bioorg Med Chem
; 20(15): 4751-9, 2012 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22771182
16.
Addition of a cholesterol group to an HIV-1 peptide fusion inhibitor dramatically increases its antiviral potency.
Proc Natl Acad Sci U S A
; 106(14): 5801-6, 2009 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-19297617
17.
Discovery of MK-1462: GLP-1 and Glucagon Receptor Dual Agonist for the Treatment of Obesity and Diabetes.
ACS Med Chem Lett
; 13(8): 1248-1254, 2022 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35978682
18.
Viral entry inhibitors targeted to the membrane site of action.
J Virol
; 84(13): 6760-8, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20357085
19.
Structural basis for HIV-1 neutralization by a gp41 fusion intermediate-directed antibody.
Nat Struct Mol Biol
; 13(8): 740-7, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16862157
20.
DPP-IV-resistant, long-acting oxyntomodulin derivatives.
J Pept Sci
; 17(4): 270-80, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21294225